Our research

Our group explores the biosynthetic potential of cold-adapted extremophilic microorganisms, particularly Antarctic psychrophiles. We investigate their unique biosynthetic pathways, enzymatic systems, and regulatory mechanisms that link metabolic activity to stress adaptation. By studying the interplay between adaptation and secondary metabolism, we aim to uncover how life in extreme environments shapes novel biochemical capabilities.

Our research also delves into the biodiversity, taxonomy, and evolutionary dynamics of Antarctic microbiota. Through phylogenetic and genomic analyses, we aim to map the diversity of psychrophilic bacteria and uncover their evolutionary strategies for survival in one of Earth's most challenging environments. This work expands our understanding of microbial evolution, ecology, and adaptation in extreme ecosystems.

We are committed to uncovering and characterizing bioactive compounds and enzymes produced by psychrophilic microorganisms. These cold-adapted biomolecules exhibit distinctive structural and functional features that enable activity under low-temperature conditions, offering new opportunities for biotechnological and biomedical innovation. Our goal is to translate the unique chemistry of extremophiles into practical applications across health, agriculture, and environmental biotechnology.

See the Publications section for more information.

Our projects are funded by the Czech Science Foundation (GACR) and the Grant Agency of Masaryk University (GAMU).